Lisa（曼迪·摩尔 Mandy Moore 饰）和Kate（克莱尔·霍尔特 Claire Holt 饰）两姐妹在墨西哥海岸度假，她们在海底观鲨铁笼中潜水观赏鲨鱼时，牵连铁笼的绳子突然断裂，观鲨笼掉落到47米深的海底
由于所存氧气不多，她们只有一个小时的时间逃脱牢笼回到水面 而此时，大白鲨也在她们周围游弋着 47米深的海底一片漆黑，只能通过手电筒观察铁笼外面的情况 水面上工作人员的声音时有时无，救援队也迟迟不见踪影，姐妹俩都非常害怕 面对仅剩的氧气，她们必须马上做出选择才有一线生机 为了避开鲨鱼活着游出水面，姐妹两人与鲨鱼之间展开了一场斗智斗勇扣人心弦的生死较量……
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